Gene
tecrb
- ID
- ZDB-GENE-030131-5154
- Name
- trans-2,3-enoyl-CoA reductase b
- Symbol
- tecrb Nomenclature History
- Previous Names
-
- tecr
- cb250 (1)
- gpsn2
- mg:db03b10
- sb:cb250
- wu:fj63b12
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable oxidoreductase activity. Predicted to be involved in very long-chain fatty acid biosynthetic process. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including digestive system; eye; forebrain; musculature system; and solid lens vesicle. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 14. Orthologous to human TECR (trans-2,3-enoyl-CoA reductase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb250 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 14 | Alliance | Intellectual developmental disorder, autosomal recessive 14 | 614020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal | 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase | TECR-like, N-terminal domain | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q7T390
|
308 | ||||
|
UniProtKB:A0A8M9QLQ8
|
348 |
Interactions and Pathways
No data available
Plasmids
No data available